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pentobarbital will reduce the level or effect of capivasertib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Solid or reasonable CYP3A inducers reduce capivasertib publicity, which can lower efficacy.pentobarbital will minimize the level or impact of diclofenac by influencing hepatic enzyme CYP2C9/